Meta-Analysis
Nonhormonal Vaginal Therapy Shows Promise
This meta-analysis of randomized trials compared vaginal radiofrequency with vaginal estrogen for postmenopausal sexual dysfunction related to genitourinary syndrome of menopause. Radiofrequency showed a modest improvement in overall sexual function scores, but the authors emphasized that longer-term durability and broader safety evidence are still needed.
Citation
Diniz AF, Ciuffatelli MX, Queiroz LF, Lemos M, Peloggia A. Radiofrequency versus vaginal estrogen for menopausal sexual dysfunction: a systematic review and meta-analysis of randomized clinical trials. Sex Med Rev. 2026;14(1):qeag013. doi:10.1093/sxmrev/qeag013.
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