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Melatonin: A Boost for Menopausal Bone, Sleep, and Well-being?

This systematic review and meta-analysis suggests that melatonin supplementation may improve bone mineral density, sleep quality, and overall quality of life in menopausal women. However, as most studies used combination therapies, further research is needed to confirm melatonin's independent effects and optimal dosage.

Du J, Tan Y. A systematic review and meta-analysis of randomized controlled trials investigated the effects of melatonin supplementation on bone mineral density, quality of life, and sleep in menopausal women. Front Nutr. 2026 Jan 29;13:1687221. doi: 10.3389/fnut.2026.1687221. PMID: 41693954.

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