As an Amazon Associate, PauseAndFlourish earns from qualifying purchases.Product prices and availability are accurate as of the date reviewed.

PauseAndFlourishMenopause Wellness Reviews & Guidance

Meta-Analysis

Hormone Therapy and Phytoestrogens May Ease Menopausal Mood Symptoms

A review of 51 hormone-therapy trials and 16 phytoestrogen trials found associations with improved mood and anxiety symptoms in menopausal women. Effects differed by symptom and subgroup, and some reported findings did not remain significant after correction, so treatment choices should remain individualized.

Citation

Shou M, Ye M, Lou C, Chen X, Yao Y, Yan J, Zhou W, Fu Z, Liu Z. Efficacy of hormone therapy and phytoestrogens on the psychological symptoms of menopausal women: a systematic review, meta-analysis, and trial sequential analysis. Front Med (Lausanne). 2026 Jul 10;13:1855845. doi:10.3389/fmed.2026.1855845. PMID: 42500528.

View Source