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Gut Microbiota Interventions Offer New Hope for Postmenopausal Bone Health

This comprehensive review highlights the emerging role of gut microbiota in regulating bone metabolism in postmenopausal women, operating through the brain-gut-bone axis, immune modulation, and metabolic byproducts such as short-chain fatty acids. Dietary interventions, probiotics, and prebiotics show promise as accessible, non-hormonal strategies for preventing and managing postmenopausal osteoporosis.

Lin Y, Zheng J, Hu D, Ying Y, Zhu Y, Chen Z. Modulating the gut ecosystem dietary, probiotic, and novel interventions for bone health in postmenopausal women. Front Immunol. 2026 Jul 3;17:1814866. doi: 10.3389/fimmu.2026.1814866. PMID: 42490818.

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