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PauseAndFlourishMenopause Wellness Reviews & Guidance

Cross-Sectional

Fatigue and Exhaustion Top Perimenopause Symptoms Globally

A global survey of over 17,000 women found a disconnect between recognized perimenopause symptoms and actual experiences. While hot flashes were the most recognized symptom, women aged 35 and older most frequently reported fatigue, physical and mental exhaustion, and irritability as their primary challenges during late perimenopause.

Citation

Hedges MS, Hewings-Martin Y, Karam J, Castaneda R, Cunningham AC, Xu Y, Zhaunova L, Faubion SS, Shufelt CL. Global perspectives on perimenopause: a digital survey of knowledge and symptoms using the Flo application. Menopause. 2026 Jul 1;33(7):789-798. doi: 10.1097/GME.0000000000002730. PMID: 41603602.

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